*Denotes Equal Contribution
#Denotes Corresponding Author
Publications from the University of Tennessee-Knoxville
17. Sword, T.T.; Barker, J.W.; Spradley, M.; Chen, Y.; Petzold, C.J.; Bailey, C.B.# “Expression of Blue Pigment Synthetase A from Streptomyces lavenduale Reveals Insights on the Effects of Refactoring Biosynthetic Megasynthases for Heterologous Expression in Escherichia coli.” In Revision.
16. Dinglasan, J.L.N.*; Sword, T.T.*; Barker, J.W.; Doktycz, M.J.#; Bailey, C.B.#. “Investigating and Optimizing the Lysate-based Expression of Nonribosomal Peptide Synthetases using a Reporter System.” ACS Synthetic Biology, 2023.
15. Drufva, E.E.; Sword, T.T.; Bailey, C.B.#“Metabolic Engineering of Actinomycetes for Natural Product Discovery.” Actinomycetes: Diversity, Ecology, and Drug Discovery. Rai, Ravishankar and Bai A, Jamuna (Eds.) Springer Singapore, 2022.
14. Drufva, E.E.; Spengler, N.; Bailey, C.B.# “Site Directed Mutagenesis of Modular Polketide Synthase Ketoreductase Domains for Altered Stereochemical Control” ChemBioChem, 2021. DO1: 22, 7, 1150.
13. Drufva, E.E.; Hix, E.G.; Bailey, C.B.# “Site Directed Mutagenesis as a Precision Tool to Enable Synthetic Biology with Engineered Modular Polyketide Synthases” Synthetic and Systems Biotechol. 2020, 5, 62.
Postdoctoral Publications (UC Berkeley, Lawrence Berkeley National Laboratory, and the Joint BioEnergy Institute):
12. Zargar, A.; Lal, R.; Valencia, L.; Wang, J.; Backman, T.W.H.; Cruz-Morales, P.; Kothari, A.; Werts, M.; Wong, A.R.; Bailey, C.B.; Loubat, A.; Yuzhong, L.; Benites, V.; Chang, S.; Hernandez, A.C.; Barajas, J.F.; Thompson, M.G.; Barcelos, C.; Anayah, R.; Garcia Martin, H.; Mukhopadhayay, A.; Baidoo, E.; Katz, L.; Keasling, J.D. Chemoinformatic-Guided Engineering of Polyketide Synthases. J. Am. Chem. Soc. 2020, 142, 22, 9896.
11. Barajas, J.F.; Wehrs, M.; To, M.; Cruickshanks, L.; Urban, R.; McKee, A.; Gladden, J.; Goh, E.; Brown, M.E.; Carothers, J.M.; Mukhopadhyay, A.; Keasling, J.D.; Fortman, J.L.; Singer, S.W.,# Bailey, C.B.# Isolation and Characterization of Microbial Cellulase Producers for Biomass Deconstruction: a Microbiology Laboratory Course. J. Microbiol. Biol. Ed. 2019, 20, 2.
10. Thompson, M.G.;* Sedghatian, N.;* Barajas, J.F.; Wehrs, M.; Bailey, C.B.; Kaplan, N.; Hillson, N.J.; Mukhopadhyay, A.; Keasling, J.D. Isolation and Characterization of Novel Mutations in the pSC101 Origin that Increase Copy Number. Sci. Rep. 2018, 8, 1590.
9. Yuzawa, S.; Bailey, C.B.; Fuji, T.; Jocic, R.; Barajas, J.F.; Benites, V.T.; Baidoo, E.E.; Chen, Y.; Petzold, C.J.; Katz, L.; Keasling, J.D. Heterologous Gene Expression of N-Terminally Truncated Variants of LipPKS1 Suggests a Functionally Critical Structural Motif in the N-terminus of Modular Polyketide Synthases. ACS Chem. Biol. 2017, 12, 2725.
8. Eng, C.H.;* Backman, T.W.H.;* Bailey, C.B.; Magnan, C.; García Martín, H.; Katz, L.; Baldi, P.; Keasling, J.D. ClusterCAD: a Computational Platform for Type I Polyketide Synthase Design. Nucl. Acid. Res. 2017, gx893.
7. Barajas, J.F.;* Blake-Hedges, J.M.;* Bailey, C.B.;* Curran S.; Keasling, J.D. Engineered Polyketides: Synergy Between Protein and Host Level Engineering. Synthetic and Systems Biotechnol. 2017, 166, 147.
6. Zargar, A.; Bailey, C.B.; Haushalter, R.W.; Eiben, C.B., Katz, L; Keasling, J.D. Leveraging Microbial Biosynthetic Pathways for the Generation of ‘Drop In’ Biofuels. Curr. Opin. Biotechnol. 2017, 45, 156.
Doctoral Publications (The University of Texas at Austin):
5. Wagner, D.T.;* Zeng, J.;* Bailey, C.B.;* Gay, D.C.; Yuan, F.; Manion, H.R.; Keatinge-Clay, A.T. Structural and Functional Trends in Dehydrating Bimodules from trans-Acyltransferase Polyketide Synthases. Structure. 2017, 25, 1.
4. Bailey, C.B.; Pasman, M.E.; Keatinge-Clay, A.T. Substrate Structure-Activity Relationships Guide Rational Engineering of Stereocontrol in Modular Polyketide Synthase Ketoreductases. ChemComm. 2016, 52, 792.
3. Brantley, J.N.; Bailey, C.B.; Cannon, J.R.; Clark, K.A.; Vanden Bout, D.A., Broadbelt, J.S., Keatinge-Clay, A.T., Bielawski, C.W. Mechanically Modulating the Photophysical Properties of Fluorescent Protein Biocomposites: New Classes of Ratio- and Intensiometric Sensors. Angew. Chem. Int. Ed. 2014, 126, 5088.
2. Brantley, J.N.; Bailey, C.B.; Wiggins, K.M.; Keatinge-Clay, A.T., Bielawski, C.W. Mechanobiochemistry: Harnessing Biomacromolecules for Force Responsive Materials. Polym. Chem., 2013, 4, 3916.
1. Harper, A.D.; Bailey, C.B.; Edwards, A.D.; Detelich, J.F.; Keatinge-Clay, A.T. Preparative in Vitro Biocatalysis of Triketide Lactone Chiral Building Blocks. ChemBioChem, 2012, 13, 2200.